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Best friends Jesse and Chester awaken with hangovers and no memory of the previous night. Their television is on, showing a program about animals using twigs and rocks as tools to get food. In the program is a monkey nicknamed Harrison. Their refrigerator is filled with containers of chocolate pudding, and the answering machine contains an angry message from their twin girlfriends Wilma and Wanda as to their whereabouts. The two also learn they have almost been fired from their jobs. They emerge from their home to find Jesse's car missing, and with it their girlfriends' first-anniversary presents. This prompts Jesse to ask the film's titular question: "Dude, where's my car?"